1. Rho S., Kobayashi I., Oguri-Nakamura E., Ando K., Fujiwara M., Kamimura N., Hirata H., Iida A., Iwai Y., Mochizuki N., Fukuhara S. (Corresponding author). Rap1b promotes Notch signal-mediated hematopoietic stem cell development by enhancing integrin-mediated cell adhesion. Dev Cell In press.
  2. *Noishiki C., *Yuge S., Ando K., Wakayama Y., Mochizuki N., Ogawa R., Fukuhara S. (Corresponding author). Live imaging of angiogenesis during cutaneous wound healing in adult zebrafish. Angiogenesis In press. *Equal contribution.
  3. Ando K., Wang W., Peng D. Chiba A., Barske L., Crump J.G., Stainier D.Y.R., Lendahl U., Lagendijk A., Koltowska K., Hogan B.M., Fukuhara S., Mochizuki N., Betsholtz C. Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling. Development In press.


  1. Rho S., Ando K., Fukuhara S. (Corresponding author). Dynamic regulation of vascular permeability by vascular endothelial cadherin-mediated endothelial cell-cell junctions. J. Nippon Med. Sch. 84 (4): 148-159 (2017).
  2. Takara K., Eino D., Ando K., Yasuda D., Naito H., Tsukada Y., Iba T., Wakabayashi T., Muramatsu F., Kidoya H., Fukuhara S., Mochizuki N., Ishii S., Kishima H., Takakura N. Lysophosphatidic acid receptor 4 activation augments drug delivery in tumors by tightening endothelial cell-cell contact. Cell Reports 20 (9): 2072-2086 (2017).
  3. Miura K., Nojiri T., Akitake Y., Ando K., Fukuhara S., Zenitani M., Kimura T., Hino J., Miyazato M., Hosoda H., Kangawa K. CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading. Biochem. J. 474: 1897-1918 (2017).
  4. Nakajima H., Yamamoto K., Agarwala S., Terai K., Fukui H., Fukuhara S., Ando K., Miyazaki T., Yokota Y., Schmelzer E., Belting H.-G., Affolter M., Lecaudey V., Mochizuki N. Flow-dependent endothelial YAP regulation that contributes to vessel maintenance. Dev. Cell 40 (6): 523-536 (2017).
  5. Chiba A., Watanabe-Takano H., Terai K., Fukui H., Miyazaki T., Uemura M., Hashimoto H., Hibi M., Fukuhara S., Mochizuki N. Osteocrin, a peptide secreted from the heart and other tissues, contributes to cranial osteogenesis and chondrogenesis in zebrafish. Development 144:334-344 (2017).


  1. Ando K., Fukuhara S. (Co-corresponding author), Izumi N., Nakajima H., Fukui H., Kelsh R.N., Mochizuki N. Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish. Development 143:1328-1339 (2016).
  2. Chávez-Vargas L., Adame-García S.R., Cervantes-Villagrana R.D., Castillo-Kauil A., Bruystens J.G.H., Fukuhara S., Taylor S.S., Mochizuki N., Reyes-Cruz G., Vázquez-Prado J. Protein kinase A (PKA) Type I interacts with P-Rex1, a Rac guanine nucleotide exchange factor: Effect on PKA localization and P-Rex1 signaling. J. Biol. Chem. 291: 6182-6199 (2016).


  1. Wakayama Y., Fukuhara S. (Corresponding author), Ando K., Matsuda M., Mochizuki N. Cdc42 mediates Bmp-induced sprouting angiogenesis through Fmnl3-driven assembly of endothelial filopodia in zebrafish. Dev. Cell 32: 109-122 (2015).
  2. Kashiwada T., Fukuhara S. (Co-corresponding author), Terai K., Tanaka T., Wakayama Y., Ando K., Nakajima H., Fukui H., Yuge S., Saito Y., Gemma A., Mochizuki N. -Catenin-dependent transcription is central to Bmp-mediated formation of venous vessels. Development 142: 497-509 (2015).
  3. Fukuhara S., Fukui H., Wakayama Y., Ando K., Nakajima H., Mochizuki N. Looking back and moving forward: Recent advances in understanding of cardiovascular development by imaging of zebrafish. Dev. Growth Differ. 57: 333-340 (2015).
  4. Yokota Y., Nakajima H., Wakayama Y. Muto A., Kawakami K. Fukuhara S., Mochizuki N. Endothelial Ca2+ oscillations reflect VEGFR signaling-regulated angiogenic capacity in vivo. eLife 4 : e08817 (2015).
  5. Kim J.-D., Park K.-E., Ishida J., Kako K., Hamada J., Kani S., Takeuchi M., Namiki K., Fukui H.,Fukuhara S., Hibi M., Kobayashi M., Kanaho Y., Kasuya Y., Mochizuki N., Fukamizu A. PRMT8 as a phospholipase maintains dendrite formation of Purkinje cells. Science Advances 1: e1500615 (2015).
  6. Sugihara K., Nishiyama K., Fukuhara S., Uemura A., Arima S., Kobayashi R., Kohn-Luque A., Mochizuki N., Suda T., Ogawa H., Kurihara H. Autonomy and non-autonomy of angiogenic cell movements revealed by experiment-driven mathematical modeling. Cell Reports 13: 1814-1827 (2015).
  7. Hongu T., Funakoshi Y., Fukuhara S., Suzuki T., Sakimoto S., Takakura N., Ema M., Takahashi S., Itoh S., Kato M., Hasegawa H., Mochizuki N., Kanaho Y. Arf6 regulates tumor angiogenesis and growth through HGF-induced endothelial 1 integrin recycling. Nat. Commun. 6: 6925 (2015).
  8. Vanhollebeke B., Stone O., Bostaille N., Cho C., Zhou Y., Maquet E., Gauquier A., Cabochette P.,Fukuhara S., Mochizuki N., Nathans J., Stainier D.Y.R. Tip cell specific requirement for an atypical Gpr124 and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis. eLife 4 : e06489 (2015).
  9. Mikelis C.M., Simaan M., Ando K., Fukuhara S., Sakurai A., Amornphimoltham P., Masedunskas A., Weigert R., Chavakis T., Adams R., Offermanns S., Mochizuki N., Zheng Y., Gutkind J.S. RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock. Nat. Commun. 6: 6725 (2015).


  1. Fukui H., Terai K., Nakajima H., Chiba A., Fukuhara S., Mochizuki N. S1P-Yap1 signaling regulates endoderm formation required for cardiac precursor cell migration in zebrafish. Dev. Cell 31: 128-136 (2014).
  2. Fukuhara S. (Co-corresponding author), Zhang J., Yuge S., Ando K., Wakayama Y., Sakaue-Sawano A., Miyawaki A., Mochizuki N. Visualizing the cell-cycle progression of endothelial cells in zebrafish. Dev. Biol. 393: 10-23 (2014).
  3. Odagiri H., Kadomatsu T., Endo M., Masuda T., Morioka M.S., Fukuhara S., Miyamoto T., Kobayashi E., Miyata K., Aoi J., Horiguchi H., Nishimura N., Terada K., Yakushiji T., Manabe I., Mochizuki N., Mizuta M., Oike Y. The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin 51, p38 MAPK, and matrix metalloproteinases. Sci. Signal. 7: ra7 (2014).
  4. Nakajima K., Shibata Y., Hishikawa Y., Suematsu T., Mori M., Fukuhara S., Koji T., Sawase T., Ikeda T. Coexpression of Ang1 and Tie2 in odontoblasts of mouse developing and mature teeth―a new insight into dentinogenesis. Acta Histochem. Cytochem. 47: 19-25 (2014).


  1. Ando K., Fukuhara S. (Co-corresponding author), Moriya T., Obara Y. Nakahata N., Mochizuki N. Rap1 potentiates endothelial cell junctions by spatially controlling myosin II activity and actin organization. J. Cell Biol. 202: 901-916 (2013).
  2. Kwon H.B., Fukuhara S., Asakawa K., Ando K., Kashiwada T., Kawakami K., Hibi M., Kwon Y.G., Kim K.W., Alitalo K., Mochizuki N. The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 signal in zebrafish. Development 140: 4081-4090 (2013).
  3. Mikelis C.M., Palmby T.R., Simaan M., Li W., Szabo R., Lyons R., Martin D., Yagi H., Fukuhara S., Chikumi H., Galisteo R., Mukouyama Y., Bugge T.H., Gutkind J.S. PDZ-RhoGEF and LARG are essential for embryo development, and provide a link between thrombin and LPA receptors and Rho activation. J. Biol. Chem. 288: 12232-12243 (2013).
  4. Fukuhara S., Mochizuki N. Signaling pathways regulating endothelial cell-cell junctions as a barrier to tumor metastasis. In “Tight junctions in cancer metastasis”, Springer, 275-289 (2013).


  1. Fukuhara S. (Co-corresponding author), Simmons S., Kawamura S., Inoue A., Orba Y., Tokudome T., Sunden Y., Arai Y., Moriwaki K., Ishida J., Uemura A, Kiyonari H., Abe T., Fukamizu A., Hirashima M., Sawa H., Aoki J., Ishii M, Mochizuki N. The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. J. Clin. Invest. 122: 1416-1426 (2012).
  2. Kusuhara S., Fukushima Y., Fukuhara S., Jakt L.M., Okada M., Shimizu Y., Hata M., Nishida K., Negi A., Hirashima M., Mochizuki N., Nishikawa S., Uemura A. Arhgef15 promotes retinal angiogenesis by mediating VEGF-induced Cdc42 activation and potentiating RhoJ inactivation in endothelial cells. PLoS One 7: e45858 (2012).
  3. Takenouchi T., Iwamaru Y., Imamura M., Fukuhara S., Sugama S., Sato M., Mochizuki N., Hashimoto M., Yokoyama T., Mohri S., Kitani H. Cytochalasin D enhances the accumulation of a protease-resistant form of prion protein in ScN2a Cells: Involvement of PI3 kinase/Akt signaling pathway. Cell Biol. Int. 36: 1223-1231 (2012).
  4. Endo M., Nakano M., Kadomatsu T., Fukuhara S., Kuroda H., Mikami S., Hato T., Aoi J., Horiguchi H., Miyata K., Odagiri H., Masuda T., Harada M., Horio H., Hishima T., Nomori H., Ito T., Yamamoto Y., Minami T., Okada S., Takahashi T., Mochizuki N., Iwase H., Oike Y. Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis. Cancer Res. 72: 1784-1794 (2012).
  5. Makita N., Seki A., Sumitomo N., Chkourko H., Fukuhara S., Watanabe H., Shimizu W., Bezzina C.R., Hasdemir C., Mugishima H., Makiyama T., Baruteau A., Baron E., Horie M., Hagiwara N., Wilde A.A., Probst V., Le Marec H., Roden D.M., Mochizuki N., Schott J.J., Delmar M. A connexin 40 mutation associated with a malignant variant of progressive familial heart block type-1. Circ. Arrhythm. Electrophysiol. 5: 163-172 (2012).


  1. Minami M., Koyama T., Wakayama Y., Fukuhara S. (Corresponding author), Mochizuki N. EphrinA/EphA signal facilitates insulin-like growth factor-I-induced myogenic differentiation through suppression of the Ras/extracellular signal-regulated kinase 1/2 cascade in myoblast cell lines. Mol. Biol. Cell 22: 3508-3519 (2011).
  2. Zhang J., Fukuhara S. (Co-corresponding author), Sako K., Takenouchi T., Kitani H., Kume T., Koh G.Y., Mochizuki N. Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of -catenin. J. Biol. Chem. 286: 8055-8066 (2011).


  1. Noda K., Zhang J., Fukuhara S. (Co-corresponding author), Kunimoto S., Yoshimura M., Mochizuki N. Vascular endothelial-cadherin stabilizes at cell-cell junctions by anchoring to circumferential actin bundles through - and -catenins in cyclic AMP-Epac-Rap1 signal-activated endothelial cells. Mol. Biol. Cell 21: 584-596 (2010).
  2. Fukuhara S. (Corresponding author), Sako K., Noda K., Zhang J., Minami M., Mochizuki N. Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis. Histol. Histopathol. 25: 387-396 (2010).
  3. Fujimoto C., Ozeki H., Uchijima Y., Suzukawa K., Mitani A., Fukuhara S., Nishiyama K., Kurihara Y., Kondo K., Aburatani H., Kaga K., Yamasoba T., Kurihara H. Establishment of mice expressing EGFP in the placode-derived inner ear sensory cell lineage and FACS-array analysis focused on the regional specificity of the otocyst. J. Comp. Neurol. 518: 4702-4722 (2010).


  1. Tabata M., Kadomatsu T., Fukuhara S., Miyata K., Ito Y., Endo M., Urano T., Zhu H.J., Tsukano H., Tazume H., Kaikita K., Miyashita K., Iwawaki T., Shimabukuro M., Sakaguchi K., Ito T., Nakagata N., Yamada T., Katagiri H., Kasuga M., Ando Y., Ogawa H., Mochizuki N., Itoh H., Suda T., Oike Y. Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance. Cell Metabolism 10: 178-188 (2009).
  2. Fukuhara S., Sako K., Noda K., Nagao K., Miura K., Mochizuki N. Tie2 is tied at the cell-cell contacts and to extracellular matrix by Angiopoietin-1. Exp. Mol. Med. 41: 133-139 (2009).
  3. Sako K., Fukuhara S. (Corresponding author), Minami T., Hamakubo T., Song H., Kodama T., Fukamizu A., Gutkind J.S., Koh G.Y., Mochizuki N. Angiopoietin-1 induces Krüppel-Like Factor 2 expression through a phosphoinositide 3-kinase/AKT-dependent activation of myocyte enhancer factor 2. J. Biol. Chem. 284: 5592-5601 (2009).


  1. Fukuhara S. (Co-corresponding author), Sako K., Minami T., Noda K., Kim H.Z., Kodama T., Shibuya M., Takakura N., Koh G.Y., Mochizuki N. Differential function of Tie2 at cell-cell contacts and cell-substratum contacts regulated by angiopoietin-1. Nat. Cell Biol. 10: 513-526 (2008).
  2. Mukai H., Kikuchi M., Fukuhara S., Kiso Y., Munekata E. Cryptide signaling: amphiphilic peptide-induced exocytosis mechanisms in mast cells. Biochem. Biophys. Res. Commun. 375: 22-26 (2008).
  3. Makita N., Behr E., Shimizu W., Horie M., Sunami A., Crotti L., Schulze-Bahr E., Fukuhara S., Mochizuki N., Makiyama T., Itoh H., Christiansen M., McKeown P., Miyamoto K., Kamakura S., Tsutsui H., Schwartz P.J., George Jr A. L., Roden D. M. The E1784K mutation in SCN5A is associated with mixed clinical phenotype of type 3 long QT syndrome. J. Clin. Invest. 118: 2219-2229 (2008).
  4. Yasuda N., Miura S., Akazawa H., Tanaka T., Qin Y., Kiya Y., Imaizumi S., Fujino M., Ito K., Zou Y., Ge J., Fukuhara S., Kunimoto S., Mochizuki N., Fukuzaki K., Sato T., Nakaya H., Saku K., Komuro I. Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation. EMBO Rep. 9: 179-186 (2008).


  1. Kamide K., Kokubo Y., Fukuhara S., Hanada H., Yang J., Kada A., Nagura J., Takiuchi S., Horio T., Kawano Y., Okayama A., Tomoike H., Miyata T. Protein Tyrosine Kinase 2β as a Candidate Gene for Hypertension. Pharmacogenet. Genomics.17: 931-939 (2007).
  2. Yamaguchi Y., Nagase T., Tomita T., Nakamura K., Fukuhara S., Amano T., Yamamoto H., Ide Y., Suzuki M., Teramoto S., Asano T., Kangawa K., Nakagata N., Ouchi Y., Kurihara H. -defensin overexpression induces progressive muscle degeneration in mice. Am. J. Physiol. Cell Physiol. 292: C2141-C2149 (2007).


  1. Fukuhara S., Sakurai A., Yamagishi A., Sako K., Mochizuki N. Vascular endothelial cadherin-mediated cell-cell adhesion regulated by a small GTPase, Rap1. J. Biochem. Mol. Biol. 39: 132-139 (2006).
  2. Sakurai A., Fukuhara S., Yamagishi A., Sako K., Kamioka Y., Masuda M., Nakaoka Y., Mochizuki N. MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin–mediated cell adhesion. Mol. Biol. Cell 17: 966-976 (2006).


  1. Somekawa S., Fukuhara S., Nakaoka Y., Fujita H., Saito Y., Mochizuki N. Enhanced functional gap junction neoformation by PKA-dependent and Epac-dependent signals downstream of cAMP in cardiac myocytes. Circ. Res. 97: 655-662 (2005).
  2. Ohkawara H., Ishibashi T., Sakamoto T., Sugimoto K., Nagata K., Yokoyama K., Sakamoto N., Kamioka M., Matsuoka I., Fukuhara S., Sugimoto N., Takuwa Y., Maruyama Y. Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells. J. Biol. Chem. 280: 10182-10188 (2005).
  3. Fujita H., Fukuhara S., Sakurai A., Yamagishi A., Kamioka Y., Nakaoka Y., Masuda M., Mochizuki N. Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied with extension of microtubules on which RapL, a Rap1-associating molecule, localizes. J. Biol. Chem. 280: 5022-5031 (2005).
  4. Fukuhara S.., Sakurai A., Sano H., Yamagishi A., Somekawa S., Takakura N., Saito Y., Kangawa K., Mochizuki N. Cyclic AMP potenciates VE-cadherin–mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway. Mol. Cell. Biol. 25: 136-146 (2005).


  1. Fukuhara S., Kurihara Y., Arima Y., Yamada N., Kurihara H. Temporal requirement of signaling cascade involving endothelin-1/endothelin receptor type A in branchial arch development. Mech. Dev. 121: 1223-1233 (2004).
  2. Kamioka Y., Fukuhara S., Sawa H., Nagashima K., Masuda M., Matsuda M., Mochizuki N. A novel dynamin-associating molecule, forming-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. J. Biol. Chem. 279: 40091-40099 (2004).
  3. Murakami M., Kataoka K., Fukuhara S., Nakagawa O., Kurihara H. Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity. Eur. J. Biochem. 271: 3330-3339 (2004).


  1. Endo A., Fukuhara S., Masuda M., Ohmori T., Mochizuki N. Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR2) identifies a central role for VEGFR2 in human aortic endothelial cell response to VEGF. J. Recept. Signal Transduct. Res. 23: 239-54 (2003).


  1. Chikumi H., Fukuhara S., Gutkind J.S. Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF and LARG, by tyrosine phosphorylation: Evidence of a role for FAK. J. Biol. Chem. 227: 12463-12467 (2002).
  2. Yamaguchi Y., Nagase T., Makita R., Fukuhara S., Tomita T., Tominaga T., Kurihara H., Ouchi Y. Identification of multiple novel epididymis-specific -defensin isoforms in the humans and mice. J. Immunol. 169: 2516-2523 (2002).


  1. Fukuhara S., Chikumi H., Gutkind J.S. RGS-containing RhoGEFs: The missing link between transforming G proteins and Rho? Oncogene 20: 1661-1668 (2001).
  2. Yamaguchi Y., Fukuhara S., Nagase T., Tomita T., Hitomi S., Kimura S., Kurihara H., Ouchi Y. A novel mouse -defensin, mBD-6, predominantly expressed in skeletal muscle. J. Biol. Chem. 276: 31510-31514 (2001).


  1. Fukuhara S., Chikumi H., Gutkind J.S. Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G12 family to Rho. FEBS Lett. 485: 183-188 (2000).
  2. Fukuhara S., Marinissen M.J., Chiariello M., Gutkind J.S. Signaling from G protein-coupled receptors to ERK5/BMK1 involves Gq and G12/13 families of heterotrimeric G proteins: Evidence for the existence of a novel Ras and Rho-independent pathway. J. Biol. Chem. 275: 21730-21736 (2000).
  3. Fukuhara S., Gutkind J.S. A new twist for the tumour suppressor hamartin. Nat. Cell Biol. 2: E76-E78 (2000).
  4. Fukuhara S., Marinissen M.J., Chiariello M. and Gutkind J.S. Signaling from G-protein-coupled receptors to the nucleus. In "Signaling networks and cell cycle control", Humana Press, 83-98 (2000).
  5. Chiang Y.J., Kole H.K., Brown K., Naramura M., Fukuhara S., Hu R.-J., Jang I.K., Gutkind J.S., Shevach E., Gu H. Cbl-b regulates the CD28 dependence of T-cell activation. Nature 403: 216-220 (2000).
  6. Murga C., Fukuhara S., Gutkind J.S. A novel role for phosphatidylinositol 3-kinase  in signaling from G protein-coupled receptors to Akt. J. Biol. Chem. 275: 12069-12073 (2000).
  7. Pirone D.M., Fukuhara S., Gutkind J.S., Burbelo P.D. SPECs, small binding proteins for Cdc42. J. Biol. Chem. 275: 22650-22656 (2000).


  1. Fukuhara S., Murga C., Zohar M., Igishi T., Gutkind J.S. A novel PDZ-domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho. J. Biol. Chem. 274: 5868-5879 (1999).
  2. Igishi T., Fukuhara S., Patel V., Katz B.-Z., Yamada K.M., Gutkind J.S. Divergent signaling pathways link focal adhesion kinase to mitogen-activated protein kinase cascades: Evidence for a role of paxillin in c-Jun NH2-terminal kinase activation. J. Biol. Chem. 274: 30738-30746 (1999).
  3. Murga C., Fukuhara S., Gutkind J.S. Novel molecular mediators in the pathway connecting by G protein-coupled receptors to MAP kinases. Trends in Endocrinology and Metabolism 10: 122-127 (1999).


  1. Fukuhara S., Mukai H., Munekata E. Characterization of neurokinin receptor types and their intracellular signaling in C1300 cells. Peptides 1997 (Proceedings of 15th American Peptide Symposium): 648-649 (1998).
  2. Fukuhara S., Shimizu M., Matsushima H., Mukai H., Munekata E. Signaling pathways via NK1 receptors and their desensitization in an AR42J cell line. Peptides 19: 1349-1357 (1998).


  1. Fukuhara S., Mukai H., Munekata E. Activin A and all-trans-retinoic acid cooperatively enhanced the functional activity of L-type Ca2+ channels in the neuroblastoma C1300 cell line. Biochem. Biophys. Res. Commun. 241: 363-368 (1997).
  2. Fukuhara S., Mukai H., Munekata E. Identification of neurokinin receptor types and intracellular signal transduction induced by them in the murine neuroblastoma C1300 cell line. Peptide Chemistry 1996 (Proceedings of 34th Japanese Peptide Symposium): 289-292 (1997).


  1. Fukuhara S., Mukai H., Kako K., Nakayama K., Munekata E. Further identification of neurokinin receptor types and mechanisms of calcium signaling evoked by neurokinins in the murine neuroblastoma C1300 cell line. J. Neurochem. 67: 1282-1292 (1996).
  2. Fukuhara S., Mukai H., Munekata E. Intracellular signal transduction involved in neurokinin receptors. Peptides 1995 (Proceedings of 14th American Peptide Symposium,): 410-411 (1996).


  1. Fukuhara S., Mukai H., Munekata E. Intracellular signal transduction induced by neurokinin receptors in C1300 cells. Peptides 1994 (Proceedings of 23rd European Peptide Symposium): 775-776 (1995).
  2. Fukuhara S., Shimizu M., Mukai H., Munekata E. Mechanisms of amylase secretion induced by neurokinins in AR42J rat pancreatic acinar cells. Peptide Chemistry 1994 (Proceedings of 32nd Japanese Peptide Symposium): 385-388 (1995).
  3. Fukuhara S., Mukai H., Munekata E. Pharmacological evidence for neurokinin receptors in murine neuroblastoma C1300 cells. Peptides 16: 211-214 (1995).
  4. Munekata E., Fukuhara S., Akutsu T., Mizushima K. The occurrence of proneurokinin B (ProNKB), a putative precursor peptide of neurokinin B (NKB), in porcine spinal cord. Peptide Chemistry 1992 (Proceedings of 2nd Japanese Symposium on Peptide Chemistry): 385-388 (1995).